TARBP2 Matched Antibody Pair

TARBP2, also known as TAR RNA binding protein 2, plays a critical role in the RNA interference pathway, a crucial cellular process that regulates gene expression. It is an integral component of the RISC-loading complex, which is essential for the maturation of microRNAs (miRNAs) and small interfering RNAs (siRNAs). By facilitating the incorporation of these small RNAs into the RNA-induced silencing complex (RISC), TARBP2 enables the degradation or translational repression of target messenger RNAs (mRNAs).

Research into TARBP2 is significant in understanding its involvement in various biological processes and its implications in diseases, particularly cancer, where alterations in RNA interference components can lead to dysregulated gene expression. Understanding the function and regulation of TARBP2 could, therefore, contribute to the development of novel therapeutic strategies targeting genetic and epigenetic dysregulation in diseases.