Three-dimensional (3D) Genomic

The study of the 3D genome is revolutionizing our understanding of genetic regulation by exploring how DNA is spatially organized within the nucleus. Unlike traditional linear genome sequencing, 3D genome research highlights the physical interactions between different genomic regions, which can significantly influence gene expression and cellular function. Techniques such as Hi-C and chromatin conformation capture are employed to map these intricate interactions, providing insights into complex biological processes and diseases. By examining the 3D genome, scientists are uncovering new mechanisms of gene regulation, paving the way for advancements in personalized medicine and therapeutic interventions.